Description

3-Chloro-6-Iodo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functionalized heterocyclic building block designed for advanced organic synthesis. Its complex molecular architecture, featuring halogen and trifluoromethyl substituents, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides, where the halogen and trifluoromethyl groups contribute to bioactivity and metabolic stability.
• Material Science Building Block: Employed in the creation of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient imidazopyridine core.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes and tools to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	3-Chloro-6-Iodo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1363405-48-4
Molecular Formula	C11H5ClF3IN2O2
Molecular Weight	416.52 g/mol
Synonyms	Ethyl 3-Chloro-6-Iodo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 3-Chloro-6-iodo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-chloro-6-iodo-8-(trifluoromethyl)-, ethyl ester; CAS 1363405-48-4; 1363405-48-4
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-6-Iodo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects with custom synthesis and scale-up services, ensuring a reliable supply of material that meets your specific project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.