Description

Methyl 5-Amino-2-Bromoisonicotinate CAS NO 1363383-38-3 is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a multifunctional scaffold with both amino and bromo substituents, enabling precise molecular construction for complex targets. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new pesticides, herbicides, and fungicides with targeted activity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and organocatalysts.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	Methyl 5-Amino-2-Bromoisonicotinate
CAS No.	1363383-38-3
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	Methyl 5-Amino-2-Bromopyridine-4-carboxylate; 2-Bromo-5-Aminopyridine-4-carboxylic Acid Methyl Ester; 5-Amino-2-Bromoisonicotinic Acid Methyl Ester; 4-Pyridinecarboxylic acid, 5-amino-2-bromo-, methyl ester; Methyl 5-Amino-2-Bromo-4-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2-Bromoisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.