Description

4-Bromomethyl-1-Boc-4-Methylpiperidine CAS NO 1363383-33-8 is a high-purity, advanced pharmaceutical intermediate featuring a versatile bromomethyl group protected by a Boc (tert-butoxycarbonyl) group. This compound is a critical building block in modern organic synthesis, enabling the efficient introduction of functionalized piperidine scaffolds into complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing piperidine or piperazine moieties.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors for antiviral and anticancer therapies.
• Kinase Inhibitor Synthesis: Serves as a crucial building block for constructing kinase inhibitors, a major class of targeted cancer therapeutics.
• Peptidomimetic Chemistry: Facilitates the creation of peptidomimetics by providing a protected, functionalized heterocyclic core structure.
• Chemical Biology & Probe Development: Employed in the design and synthesis of chemical probes for studying biological pathways and target validation.
• Agrochemical Research: Used as an intermediate in the development of new agrochemicals with specific biological activity.

Basic Information

Product Name	4-Bromomethyl-1-Boc-4-Methylpiperidine
CAS No.	1363383-33-8
Molecular Formula	C12H22BrNO2
Molecular Weight	292.21 g/mol
Synonyms	1-Boc-4-(bromomethyl)-4-methylpiperidine; tert-Butyl 4-(bromomethyl)-4-methylpiperidine-1-carboxylate; 4-Methyl-4-(bromomethyl)piperidine-1-carboxylic acid tert-butyl ester; 4-(Bromomethyl)-4-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 4-(Bromomethyl)-1-(tert-butoxycarbonyl)-4-methylpiperidine; 4-Bromomethyl-4-methylpiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-bromomethyl-4-methylpiperidine
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-1-Boc-4-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.