Description

5-Amino-6-Iodo-Pyrazine-2-Carboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both amino and iodo substituents on the pyrazine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in conductive polymers.
• Chemical Synthesis: The reactive iodo and amino groups allow for versatile cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization, enabling rapid library synthesis.
• Bioconjugation & Probe Development: Useful for labeling biomolecules or creating fluorescent probes and diagnostic agents in life science research.

Basic Information

Product Name	5-Amino-6-Iodo-Pyrazine-2-Carboxylic Acid Methyl Ester
CAS No.	1363383-24-7
Molecular Formula	C7H6IN3O2
Molecular Weight	291.05 g/mol
Synonyms	Methyl 5-Amino-6-iodopyrazine-2-carboxylate; 5-Amino-6-iodopyrazine-2-carboxylic acid methyl ester; 6-Iodo-5-aminopyrazine-2-carboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 5-amino-6-iodo-, methyl ester; Methyl 6-iodo-5-aminopyrazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-Amino-6-Iodo-Pyrazine-2-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.