Description

1-(5-Bromo-3-Nitropyridin-2-Yl)Ethanone is a high-purity, multi-functional pyridine derivative building block essential for advanced organic synthesis. This compound is valued for its reactive bromo and nitro substituents, which enable precise chemical modifications in complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development teams for creating novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used to construct complex heterocyclic structures for next-generation pesticides and herbicides.
• Material Science Research: Serves as a building block for creating functionalized ligands and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom.
• Academic & R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-(5-Bromo-3-Nitropyridin-2-Yl)Ethanone
CAS No.	1363382-81-3
Molecular Formula	C7H5BrN2O3
Molecular Weight	245.03 g/mol
Synonyms	2-Acetyl-5-bromo-3-nitropyridine; 1-(5-Bromo-3-nitropyridin-2-yl)ethan-1-one; 5-Bromo-3-nitro-2-acetylpyridine; Ethanone, 1-(5-bromo-3-nitro-2-pyridinyl)-; 2-Pyridineethanone, 5-bromo-3-nitro-; 5-Bromo-3-nitropyridin-2-yl methyl ketone
EINECS	Contact for details

Quality Control

Every batch of 1-(5-Bromo-3-Nitropyridin-2-Yl)Ethanone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.