Description

6-(Boc-Amino)-3-Azabicyclo[3.1.1]Heptane is a high-purity, protected amine derivative featuring a rigid bicyclic scaffold, making it a valuable building block in advanced organic synthesis. This compound is essential for medicinal chemistry research, particularly in the development of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its constrained bicyclic structure to influence biological activity and metabolic stability.
• Peptidomimetics & PROTACs: Serves as a rigid, three-dimensional scaffold to replace peptide bonds or as a linker component in Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Ligand & Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein-protein interactions due to its amine handle for further conjugation.
• Material Science: Potential monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties.

Basic Information

Item	Detail
Product Name	6-(Boc-Amino)-3-Azabicyclo[3.1.1]Heptane
CAS No.	1363382-46-0
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl (3-azabicyclo[3.1.1]heptan-6-yl)carbamate; 3-Azabicyclo[3.1.1]heptane-6-carboxamide, N-(1,1-dimethylethoxy)-; 6-N-Boc-amino-3-azabicyclo[3.1.1]heptane; 6-(tert-Butoxycarbonylamino)-3-azabicyclo[3.1.1]heptane; BOC-3-Azabicyclo[3.1.1]heptan-6-amine; 6-Amino-3-azabicyclo[3.1.1]heptane, N-BOC-protected
EINECS	Contact for details

Quality Control

Our 6-(Boc-Amino)-3-Azabicyclo[3.1.1]Heptane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.