Description

6-Bromo-1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor in the development of novel pharmaceutical candidates, particularly kinase inhibitors and other biologically active molecules. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and life science industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of small molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Core scaffold for constructing potent and selective kinase inhibitors due to its privileged pyrazolopyridine structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and cellular signaling.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke compounds and APIs under cGMP conditions.

Basic Information

Product Name	6-Bromo-1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylic Acid
CAS No.	1363382-29-9
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid; 1363382-29-9; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid; 6-Bromopyrazolo[4,3-b]pyridine-3-carboxylic acid; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.