Description

5-[(tert-Butoxy)Carbonyl]-4H,5H,6H,7H-Thieno[3,2-C]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused thienopyridine heterocyclic structure. This compound is of significant value in medicinal chemistry as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Employed in the development and scale-up processes for new active pharmaceutical ingredients, especially those containing the thieno[3,2-c]pyridine core.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for investigating biological mechanisms and target validation.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	5-[(tert-Butoxy)Carbonyl]-4H,5H,6H,7H-Thieno[3,2-C]Pyridine-3-Carboxylic Acid
CAS No.	1363382-28-8
Molecular Formula	C13H17NO4S
Molecular Weight	283.34 g/mol
Synonyms	5-(Boc)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-3-carboxylic acid; 3-Carboxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 3-carboxy-4,7-dihydro-5H-thieno[3,2-c]pyridine-5-carboxylate; 5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-3-carboxylic acid; Boc-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-[(tert-Butoxy)Carbonyl]-4H,5H,6H,7H-Thieno[3,2-C]Pyridine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.