Description

Methyl 1-(Pyrazin-2-Yl)Cyclopropanecarboxylate CAS NO 1363382-27-7 is a high-value, synthetically versatile heterocyclic building block featuring a cyclopropane ring fused with a pyrazine moiety. This compound is critical for research and development in advanced organic synthesis, serving as a key precursor for complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the biological activity of the pyrazine and strained cyclopropane rings.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and functional polymers due to its rigid, conjugated structure.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, multi-ring heterocyclic systems.

Basic Information

Item	Details
Product Name	Methyl 1-(Pyrazin-2-Yl)Cyclopropanecarboxylate
CAS No.	1363382-27-7
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	Methyl 1-(pyrazin-2-yl)cyclopropanecarboxylate; 1-Pyrazin-2-ylcyclopropanecarboxylic acid methyl ester; Methyl 1-pyrazin-2-ylcyclopropanecarboxylate; 1-(2-Pyrazinyl)cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 1-(2-pyrazinyl)-, methyl ester; 1363382-27-7; Methyl 1-(2-pyrazinyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-(Pyrazin-2-Yl)Cyclopropanecarboxylate is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment, supporting compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.