Description

3-(1-Methylethyl)-1,3-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 3-Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine dicarboxylate structure. This compound is critical for ensuring the precise synthesis and consistent quality of complex active pharmaceutical ingredients (APIs) in regulated manufacturing processes. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Process Chemistry & Scale-Up: Used in route scouting, optimization, and the commercial-scale production of Active Pharmaceutical Ingredients (APIs) under GMP conditions.
• Medicinal Chemistry Research: Employed in the design and synthesis of novel compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Manufacturing: Utilized in the production of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Contract Research & Development (CRO/CMO): Supplied to outsourcing partners who require reliable, high-quality intermediates for client projects.

Basic Information

Product Name	3-(1-Methylethyl)-1,3-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 3-Methyl Ester
CAS No.	1363166-18-0
Molecular Formula	C16H27NO4
Molecular Weight	297.39 g/mol
Synonyms	1-tert-Butyl 3-methyl 3-isopropylpiperidine-1,3-dicarboxylate; 3-Isopropyl-1,3-piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 3-Methyl Ester; 3-(Propan-2-yl)piperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester; tert-Butyl methyl 3-isopropylpiperidine-1,3-dicarboxylate; 1,3-Piperidinedicarboxylic acid, 3-(1-methylethyl)-, 1-(1,1-dimethylethyl) 3-methyl ester
EINECS	Contact for details

Quality Control

Our 3-(1-Methylethyl)-1,3-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 3-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements, including ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.