Description

tert-Butyl3-(3-Amino-1H-Pyrazol-1-Yl)Azetidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-pyrazole hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas like kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The azetidine and amino-pyrazole motifs make it particularly valuable for synthesizing potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological targets and mechanisms.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.
• Agrochemical Research: Potential application as an intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	tert-Butyl3-(3-Amino-1H-Pyrazol-1-Yl)Azetidine-1-Carboxylate
CAS No.	1361386-63-1
Molecular Formula	C11H18N4O2
Molecular Weight	238.29 g/mol
Synonyms	1-(1-Boc-azetidin-3-yl)-1H-pyrazol-3-amine; 1-(1-(tert-Butoxycarbonyl)azetidin-3-yl)-1H-pyrazol-3-amine; tert-Butyl 3-(3-amino-1H-pyrazol-1-yl)azetidine-1-carboxylate; 3-Amino-1-(1-Boc-azetidin-3-yl)-1H-pyrazole; 1-(Azetidin-3-yl)-1H-pyrazol-3-amine, 1-Boc protected; Azetidine-1-carboxylic acid, 3-(3-amino-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester; Boc-3-(3-aminopyrazol-1-yl)azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl3-(3-Amino-1H-Pyrazol-1-Yl)Azetidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.