Description

Methyl 2-Bromo-5-Nitropyridine-4-Carboxylate, 2-Bromo-4-(Methoxycarbonyl)-5-Nitropyridine CAS NO 1361385-86-5 is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and nitrated structure makes it an indispensable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive bromo and nitro groups.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and liquid crystals with tailored electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent in probe development for studying biological pathways.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Nucleophilic Substitution: The bromine atom provides a reactive site for nucleophilic aromatic substitution, enabling further functionalization.

Basic Information

Product Name	Methyl 2-Bromo-5-Nitropyridine-4-Carboxylate, 2-Bromo-4-(Methoxycarbonyl)-5-Nitropyridine
CAS No.	1361385-86-5
Molecular Formula	C8H5BrN2O4
Molecular Weight	273.04 g/mol
Synonyms	Methyl 2-bromo-5-nitroisonicotinate; 2-Bromo-5-nitroisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-bromo-5-nitro-, methyl ester; 2-Bromo-4-(methoxycarbonyl)-5-nitropyridine; Methyl 2-bromo-5-nitropyridine-4-carboxylate; 2-Bromo-5-nitropyridine-4-carboxylic acid methyl ester; 1361385-86-5
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-5-Nitropyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.