Description

5-Bromo-3-(Trifluoromethyl)Pyrazin-2-Amine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its molecular structure, featuring both bromo and trifluoromethyl substituents on a pyrazine core, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for functionalized heterocycles used in organic electronics and ligand design for catalysis.
• Chemical Biology: Employed as a probe or labeling agent due to the reactivity of the bromine atom for further functionalization (e.g., cross-coupling reactions).
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Bromo-3-(Trifluoromethyl)Pyrazin-2-Amine
CAS No.	1360552-59-5
Molecular Formula	C5H3BrF3N3
Molecular Weight	241.99 g/mol
Synonyms	2-Amino-5-bromo-3-(trifluoromethyl)pyrazine; 5-Bromo-3-trifluoromethyl-2-pyrazinamine; 5-Bromo-3-(trifluoromethyl)-2-pyrazinamine; 1360552-59-5; 2-Pyrazinamine, 5-bromo-3-(trifluoromethyl)-; 5-Bromo-3-(trifluoromethyl)pyrazin-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(Trifluoromethyl)Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.