Description

3-Bromo-2-Chloro-5-Methylpyrazine is a high-purity halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which enables precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and electronic materials.
• Chemical Biology: Employed as a molecular probe or linker in bioconjugation and proteomics research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Methylpyrazine
CAS No.	1359828-82-2
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	2-Chloro-3-bromo-5-methylpyrazine; 5-Methyl-3-bromo-2-chloropyrazine; 3-Bromo-2-chloro-5-methyl-1,4-diazine; Pyrazine, 3-bromo-2-chloro-5-methyl-; 2-Chloro-3-bromo-5-methyl-1,4-diazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Methylpyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.