Description

Anagliptin Hydrochloride is a high-purity active pharmaceutical ingredient (API) belonging to the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It serves as a critical raw material in the formulation of advanced anti-diabetic medications, offering a targeted mechanism of action for glycemic control. This compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for type 2 diabetes mellitus.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of anti-diabetic drugs.
• Research & Development: Used in preclinical and clinical studies for new diabetes therapies.
• Formulation Development: Key component in creating various dosage forms such as tablets and capsules.
• Reference Standard: Serves as an analytical standard for quality control and regulatory testing.
• Metabolic Disorder Research: Tool for studying DPP-4 enzyme inhibition and glucose metabolism pathways.

Basic Information

Product Name	Anagliptin Hydrochloride
CAS No.	1359670-56-6
Molecular Formula	C19H21N5O2 • HCl
Molecular Weight	387.86 g/mol (free base: 351.40)
Synonyms	Anagliptin HCl; SYR-322 Hydrochloride; 2-({6-[(2R)-2-Aminopropyl]-1,2,4-triazolo[1,5-a]pyridin-2-yl}-4-methylphenol Hydrochloride; (R)-2-(6-(2-Aminopropyl)-1,2,4-triazolo[1,5-a]pyridin-2-yl)-4-methylphenol Hydrochloride; UNII-4V9H1F9Y8H; Tenelia (brand name association); DPP-4 Inhibitor Anagliptin Hydrochloride
EINECS	Contact for details

Quality Control

Our Anagliptin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.