Description

(R)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate is a high-value, chiral piperazine derivative serving as a critical synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly in the synthesis of complex molecules with specific stereochemistry. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, particularly in oncology, neurology, and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Integral to the design and synthesis of peptidomimetic compounds for drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing bespoke chemical entities.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	(R)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate
CAS No.	1359658-44-8
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	1-Boc-2-cyano-(R)-piperazine; (R)-1-(tert-Butoxycarbonyl)-2-cyanopiperazine; (R)-N-Boc-2-cyanopiperazine; (R)-2-Cyano-1-(tert-butoxycarbonyl)piperazine; tert-Butyl (R)-2-cyanopiperazine-1-carboxylate; (R)-1-Boc-2-cyanopiperazine; (R)-2-Cyanopiperazine-1-carboxylic acid tert-butyl ester; (R)-tert-Butyl 2-cyanopiperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.