Description

(S)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate CAS NO 1359658-29-9 is a high-value, chiral piperazine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in its role as a key building block for the development of novel, biologically active compounds, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and process scale-up teams working on new drug candidates, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, protease inhibitors, and other targeted therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the specific stereochemistry influences biological activity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog for constructing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and process development in fine chemical manufacturing.

Basic Information

Product Name	(S)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate
CAS No.	1359658-29-9
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	1-Boc-2-cyano-(S)-piperazine; (S)-1-(tert-Butoxycarbonyl)-2-cyanopiperazine; (S)-2-Cyano-1-(tert-butoxycarbonyl)piperazine; tert-Butyl (S)-2-cyanopiperazine-1-carboxylate; (S)-1-Boc-2-cyanopiperazine; (S)-2-Cyanopiperazine-1-carboxylic acid tert-butyl ester; (S)-N-Boc-2-cyanopiperazine; (S)-1-N-Boc-2-cyanopiperazine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-Cyanopiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.