Description

3-Bromo-7-Methoxy-1H-Pyrazolo[4,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors to create new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The pyrazolopyridine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis services and scale-up processes under cGMP conditions.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents.

Basic Information

Product Name	3-Bromo-7-Methoxy-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1357945-04-0
Molecular Formula	C7H6BrN3O
Molecular Weight	228.05 g/mol
Synonyms	3-Bromo-7-methoxy-1H-pyrazolo[4,3-b]pyridine; 7-Methoxy-3-bromo-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 3-bromo-7-methoxy-; 1357945-04-0; 3-Bromo-7-methoxypyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-7-Methoxy-1H-Pyrazolo[4,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.