Description

5-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid hydrochloride (Wx614232) is a high-purity, heterocyclic carboxylic acid hydrochloride salt, serving as a critical advanced pharmaceutical intermediate. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and fine chemical manufacturers requiring a reliable source of this complex building block.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with pyrazolopyridine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Employed in the research of compounds targeting neurological and psychiatric disorders.
• Custom Synthesis: Serves as a starting material or intermediate for contract research and manufacturing organizations (CROs/CMOs).
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.
• Academic Research: Used in university and institutional labs for heterocyclic chemistry and organic synthesis studies.

Basic Information

Product Name	5-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid hydrochloride (Wx614232)
CAS No.	1357353-51-5
Molecular Formula	C9H12ClN3O2
Molecular Weight	229.66 g/mol
Synonyms	5-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid HCl; 1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-5-methyl-, hydrochloride; WX-614232; Wx614232; 1357353-51-5; 5-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.