Description

3-Bromo-4-(Cyclopropylmethoxy)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core functionalized with bromine and a cyclopropylmethoxy group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new drug candidates and crop protection agents. Its specific structure makes it valuable for constructing complex molecules in discovery and scale-up programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new small-molecule drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the bioactivity of the pyridine moiety.
• Chemical Research & Development: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) in academic and industrial R&D labs.
• Material Science: Potential building block for functionalized ligands in catalytic systems or for creating specialty polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	3-Bromo-4-(Cyclopropylmethoxy)Pyridine
CAS No.	1357095-18-1
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	4-(Cyclopropylmethoxy)-3-bromopyridine; 3-Bromo-4-(cyclopropylmethoxy)pyridine; Pyridine, 3-bromo-4-(cyclopropylmethoxy)-; 3-Bromo-4-cyclopropylmethoxypyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Cyclopropylmethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.