Description

6-[Benzyl(Methyl)Amino]Pyridine-3-Boronic Acid is a specialized boronic acid derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those containing functionalized bipyridine or arylpyridine scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced organic electronic materials, such as those for OLEDs or sensors.
• Ligand Synthesis: Employed in the preparation of novel nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized in probe and tool compound development for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-[Benzyl(Methyl)Amino]Pyridine-3-Boronic Acid
CAS No.	1356239-98-9
Molecular Formula	C13H15BN2O2
Molecular Weight	242.09 g/mol
Synonyms	6-(Benzyl(methyl)amino)pyridine-3-boronic acid; 3-Pyridineboronic acid, 6-[benzyl(methyl)amino]-; 6-(N-Benzyl-N-methylamino)pyridine-3-boronic acid; 5-Borono-2-(N-methylbenzylamino)pyridine; 2-(Benzyl(methyl)amino)-5-boronopyridine; N-Benzyl-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (Pinacol ester precursor); B-[6-(Benzyl(methyl)amino)-3-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our 6-[Benzyl(Methyl)Amino]Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.