Description

2-(4-Boc-Piperazinomethyl)-1-Bromo-3-Fluorobenzene is a high-value, multi-functional chemical building block designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique halogenated and protected piperazine structure enables key transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a versatile scaffold for constructing novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for bioactivity and metabolic stability.
• Chemical Biology & Proteomics: Used in the development of molecular probes, affinity tags, and linker molecules for studying protein-protein interactions and enzyme function.
• Material Science: Employed in the synthesis of specialty polymers and advanced organic electronic materials where its aromatic and halogenated properties are beneficial.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-(4-Boc-Piperazinomethyl)-1-Bromo-3-Fluorobenzene
CAS No.	1355246-97-7
Molecular Formula	C₁₇H₂₄BrFN₂O₂
Molecular Weight	387.29 g/mol
Synonyms	1-Bromo-3-fluoro-2-[(4-{[(1,1-dimethylethoxy)carbonyl]amino}piperazin-1-yl)methyl]benzene; 2-[(4-{[(tert-Butoxy)carbonyl]amino}piperazin-1-yl)methyl]-1-bromo-3-fluorobenzene; 2-(4-Boc-Aminopiperazin-1-ylmethyl)-1-bromo-3-fluorobenzene; tert-Butyl 4-[(2-bromo-6-fluorobenzyl)piperazin-1-yl]carbamate; N-Boc-4-[(2-bromo-6-fluorobenzyl)piperazine]; Boc-Piperazine-Benzyl-Bromide-Fluoro Derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinomethyl)-1-Bromo-3-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.