Description

3-Chloro-2-Cyclobutylpyridine is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is valued for its unique molecular architecture, which combines a pyridine core with a chlorinated cyclobutyl substituent, enabling precise modifications in complex synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its structural features make it a critical component in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient pyridine ring.
• Chemical Biology Probes: Utilized as a molecular scaffold for designing probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Product Name	3-Chloro-2-Cyclobutylpyridine
CAS No.	1355070-82-4
Molecular Formula	C9H10ClN
Molecular Weight	167.64 g/mol
Synonyms	2-Cyclobutyl-3-chloropyridine; 3-Chloro-2-cyclobutylpyridine; Pyridine, 3-chloro-2-cyclobutyl-; 1355070-82-4
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Cyclobutylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.