Description

3-Chloro-2-Cyclopropylpyridine is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is valued for its unique molecular architecture, which combines a pyridine core with chlorinated and cyclopropyl substituents, enabling precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other synthetic transformations.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring specific chlorinated pyridine derivatives.

Basic Information

Product Name	3-Chloro-2-Cyclopropylpyridine
CAS No.	1355066-87-3
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	2-Cyclopropyl-3-chloropyridine; 3-Chloro-2-cyclopropyl-pyridine; Pyridine, 3-chloro-2-cyclopropyl-; 2-(3-Chlorocyclopropyl)pyridine (isomer); 3-Chloro-2-cyclopropanylpyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Cyclopropylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.