Description

2-Methyl-2-(Piperazin-1-Yl)Propanamide Hydrochloride is a high-purity pharmaceutical intermediate and building block with the CAS number 1354961-49-1. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical manufacturers developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or a core structural component in the manufacturing process of final APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	2-Methyl-2-(Piperazin-1-Yl)Propanamide Hydrochloride
CAS No.	1354961-49-1
Molecular Formula	C8H18N3O • HCl
Molecular Weight	207.71 g/mol (Free base: 172.25 g/mol)
Synonyms	2-Methyl-2-(piperazin-1-yl)propanamide hydrochloride; 2-Methyl-2-(1-piperazinyl)propanamide monohydrochloride; Propanamide, 2-methyl-2-(1-piperazinyl)-, hydrochloride (1:1); 1354961-49-1; UNII-9V6Q8Q4F4I; 9V6Q8Q4F4I; 2-Methyl-2-piperazin-1-yl-propionamide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(Piperazin-1-Yl)Propanamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, impurities, and other critical parameters. We support development and commercial projects requiring material that meets stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.