Description

5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazin-3-Ylmethanol Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex fused triazolo-pyrazine scaffolds, enabling structure-activity relationship (SAR) studies.
• Research & Development: Essential for academic and industrial research programs focused on developing new chemical entities with potential biological activity.
• Fine Chemical Production: Serves as a specialized raw material for contract manufacturing organizations (CMOs) producing high-value, low-volume compounds for clinical trials.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazin-3-Ylmethanol Dihydrochloride
CAS No.	1354953-17-5
Molecular Formula	C8H12Cl2N4O
Molecular Weight	251.11 g/mol
Synonyms	[1,2,4]Triazolo[4,3-a]pyrazin-3-methanol, dihydrochloride; 5H,6H,7H,8H-[1,2,4]Triazolo[4,3-a]pyrazin-3-ylmethanol dihydrochloride; 3-(Hydroxymethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine dihydrochloride; Triazolopyrazinemethanol dihydrochloride; CAS 1354953-17-5
EINECS	Contact for details

Quality Control

Our production of 5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrazin-3-Ylmethanol Dihydrochloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.