Description

((S)-3-Hydroxy-Piperidin-1-Yl)-Acetic Acid is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas requiring sophisticated chiral scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Synthesis: Used in the construction of protease inhibitor candidates for antiviral and other therapeutic applications.
• Chiral Ligand & Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Neurological & CNS Drug Research: Applied in the synthesis of compounds targeting neurological disorders and central nervous system (CNS) pathways.
• Peptidomimetic Chemistry: Integral for creating peptidomimetic structures in medicinal chemistry programs.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of chemical probes for studying biological mechanisms.

Basic Information

Product Name	((S)-3-Hydroxy-Piperidin-1-Yl)-Acetic Acid
CAS No.	1354000-55-7
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	2-[(3S)-3-Hydroxypiperidin-1-yl]acetic Acid; (S)-1-(Carboxymethyl)-3-hydroxypiperidine; (S)-3-Hydroxy-1-piperidineacetic Acid; (S)-N-Carboxymethyl-3-hydroxypiperidine; (3S)-3-Hydroxypiperidine-1-acetic Acid; (S)-3-Hydroxypiperidin-1-ylacetic Acid; (S)-HPAA; 1354000-55-7
EINECS	Contact for details

Quality Control

Our ((S)-3-Hydroxy-Piperidin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.