Description

(R)-3-Bromo-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the final product's biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Building block for developing novel, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis: Used as a precursor or ligand in asymmetric synthesis to induce chirality in target molecules.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services and scale-up production under cGMP conditions.
• Academic & R&D Laboratories: Serves as a valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-3-Bromo-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1354000-03-5
Molecular Formula	C10H18BrNO2
Molecular Weight	264.16 g/mol
Synonyms	tert-Butyl (R)-3-bromopiperidine-1-carboxylate; (R)-1-Boc-3-bromopiperidine; (R)-3-Bromo-1-N-Boc-piperidine; (R)-N-Boc-3-bromopiperidine; (3R)-3-Bromo-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine; 1-Boc-3-bromo-(R)-piperidine; (R)-3-Bromopiperidine-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (R)-3-Bromo-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97%), enantiomeric excess (typically ≥99%), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.