Description

1-(2,4-Dichloro-Benzenesulfonyl)-2-Methyl-Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its benzenesulfonyl piperazine hydrochloride structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for central nervous system (CNS) and anti-infective drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• CNS Drug Development: Serves as a core scaffold for potential therapeutics targeting neurological and psychiatric disorders.
• Anti-infective Agent Synthesis: Employed in the synthesis pathway for novel antibacterial or antifungal compounds.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for clinical trials.

Basic Information

Product Name	1-(2,4-Dichloro-Benzenesulfonyl)-2-Methyl-Piperazine Hydrochloride
CAS No.	1353986-11-4
Molecular Formula	C12H15Cl3N2O2S
Molecular Weight	365.68 g/mol
Synonyms	2-Methyl-1-[(2,4-dichlorophenyl)sulfonyl]piperazine hydrochloride; 1-(2,4-Dichlorobenzenesulfonyl)-2-methylpiperazine HCl; N-(2,4-Dichlorobenzenesulfonyl)-2-methylpiperazine hydrochloride; 2,4-Dichloro-N-(2-methylpiperazin-1-yl)sulfonyl-aniline hydrochloride; 2-Methyl-1-(2,4-dichlorophenylsulfonyl)piperazine hydrochloride; Piperazine, 1-[(2,4-dichlorophenyl)sulfonyl]-2-methyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dichloro-Benzenesulfonyl)-2-Methyl-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.