Description

4,4'-(Piperidin-3-Ylmethylazanediyl)Bis(Methylene)Dibenzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1353985-11-1. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

This specialized chemical intermediate serves as a key precursor in several high-value synthetic pathways.

• Pharmaceutical Intermediate: Primary use as a building block for novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Organic Synthesis: Utilized in research-scale and pilot-scale synthesis for constructing complex molecular architectures containing piperidine and benzonitrile motifs.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a reference standard or starting material for developing and scaling up robust API manufacturing processes.
• Biochemical Research: Potential use in developing probes or ligands for studying biological targets and pathways.

Basic Information

Product Name	4,4'-(Piperidin-3-Ylmethylazanediyl)Bis(Methylene)Dibenzonitrile Hydrochloride
CAS No.	1353985-11-1
Molecular Formula	C27H29N5 • HCl
Molecular Weight	476.02 g/mol (Free base: 439.56 g/mol)
Synonyms	4,4'-(Piperidin-3-Ylmethylazanediyl)bis(methylene)dibenzonitrile HCl; 4,4'-(3-Piperidinylmethylazanediyl)bis(methylene)dibenzonitrile hydrochloride; 4,4'-(Piperidin-3-ylmethyliminodimethylene)dibenzonitrile hydrochloride; 1353985-11-1; UNII-7J6Y4V5Z3K; 7J6Y4V5Z3K; 4,4'-(Piperidin-3-ylmethylazanediyl)bis(methylene)dibenzenecarbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4,4'-(Piperidin-3-Ylmethylazanediyl)Bis(Methylene)Dibenzonitrile Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.