Description

2-(4-Methoxy-Benzyloxymethyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its specific piperidine-based structure, which is a privileged scaffold for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical, agrochemical, and life science industries seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Reagent: Used as a versatile precursor for constructing complex nitrogen-containing heterocycles and other specialized organic molecules.
• Agrochemical Research: Serves as a structural component in the development of new pesticides, herbicides, and plant growth regulators.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Process Chemistry & Scale-up: Used in route scouting, optimization, and kilogram-to-ton scale production of target molecules under GMP or non-GMP conditions.
• Academic & Industrial R&D: A valuable reagent for universities and corporate research laboratories exploring new synthetic methodologies and chemical spaces.

Basic Information

Product Name	2-(4-Methoxy-Benzyloxymethyl)-Piperidine Hydrochloride
CAS No.	1353984-54-9
Molecular Formula	C15H23NO2 • HCl
Molecular Weight	285.81 g/mol (Free base: 249.35 g/mol)
Synonyms	2-[(4-Methoxybenzyl)oxymethyl]piperidine hydrochloride; 2-((4-Methoxybenzyloxy)methyl)piperidine HCl; Piperidine, 2-[(4-methoxyphenyl)methoxy]methyl]-, hydrochloride (1:1); 2-(4-Methoxybenzyloxymethyl)piperidine HCl; 2-(p-Methoxybenzyloxymethyl)piperidine hydrochloride; 1353984-54-9
EINECS	Contact for details

Quality Control

Our production of 2-(4-Methoxy-Benzyloxymethyl)-Piperidine Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by advanced chromatographic techniques. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.