Description

2-(3-Methyl-Piperazin-1-Ylmethyl)-Benzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Essential for academic and industrial R&D laboratories exploring new piperazine-based chemical entities.
• API Manufacturing: Serves as a controlled intermediate in the multi-step production of final active pharmaceutical ingredients under GMP conditions.

Basic Information

Product Name	2-(3-Methyl-Piperazin-1-Ylmethyl)-Benzonitrile Hydrochloride
CAS No.	1353984-20-9
Molecular Formula	C13H18N3·HCl
Molecular Weight	251.76 g/mol (Free base: 216.30 g/mol)
Synonyms	2-[(3-Methylpiperazin-1-yl)methyl]benzonitrile hydrochloride; 2-((3-Methylpiperazin-1-yl)methyl)benzonitrile HCl; 2-(3-Methyl-1-piperazinylmethyl)benzonitrile hydrochloride; Benzonitrile, 2-[(3-methyl-1-piperazinyl)methyl]-, hydrochloride; 1353984-20-9; 2-(3-Methylpiperazin-1-ylmethyl)benzonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3-Methyl-Piperazin-1-Ylmethyl)-Benzonitrile Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.