Description

(4-Amino-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold linked to a benzodioxole moiety. This compound matters as a critical building block for medicinal chemistry research and development, enabling the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential neurological activity.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Valuable building block for creating diverse compound libraries for high-throughput screening (HTS).
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays targeting specific receptors or enzymes.
• Custom Synthesis: Basis for the custom manufacturing of specialized derivatives and analogs for client-specific research needs.

Basic Information

Product Name	(4-Amino-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride
CAS No.	1353980-73-0
Molecular Formula	C13H17ClN2O3
Molecular Weight	284.74 g/mol
Synonyms	4-Amino-1-(1,3-benzodioxole-5-carbonyl)piperidine hydrochloride; 1-(Benzo[d][1,3]dioxole-5-carbonyl)piperidin-4-amine hydrochloride; 4-Amino-1-(1,3-benzodioxol-5-ylcarbonyl)piperidine HCl; 4-Amino-1-(piperonylcarbonyl)piperidine hydrochloride; 1-(Piperonylcarbonyl)-4-piperidinamine hydrochloride; 4-Amino-1-(1,3-benzodioxol-5-carbonyl)piperidine HCl; 4-Aminopiperidin-1-yl(1,3-benzodioxol-5-yl)methanone hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Amino-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.