Description

n-((3-Chloropyrazin-2-Yl)Methyl)Cyclopropanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazine and cyclopropane functional groups. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular architectures with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways in academic and industrial R&D.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and material science applications.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) providing custom synthesis services.

Basic Information

Product Name	n-((3-Chloropyrazin-2-Yl)Methyl)Cyclopropanamine Hydrochloride
CAS No.	1353979-80-2
Molecular Formula	C8H11Cl2N3
Molecular Weight	220.10 g/mol
Synonyms	1-[(3-Chloropyrazin-2-yl)methyl]cyclopropanamine hydrochloride; N-[(3-Chloro-2-pyrazinyl)methyl]cyclopropanamine hydrochloride; Cyclopropanamine, N-[(3-chloro-2-pyrazinyl)methyl]-, hydrochloride (1:1); 1-((3-Chloropyrazin-2-yl)methyl)cyclopropan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our production of n-((3-Chloropyrazin-2-Yl)Methyl)Cyclopropanamine Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and current industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.