Description

[1-(2-Chloro-Pyridine-3-Carbonyl)-Piperidin-3-Ylmethyl]-Carbamic Acid tert-Butyl Ester is a sophisticated heterocyclic building block and advanced pharmaceutical intermediate. This compound is of critical importance for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs. It is primarily needed by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators seeking to develop new therapeutic or crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material for the cGMP production of high-value target molecules for clinical trials.
• Agrochemical Intermediate: Potential application in the development of new generation pesticides and herbicides due to its heterocyclic structure.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	[1-(2-Chloro-Pyridine-3-Carbonyl)-Piperidin-3-Ylmethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353974-41-0
Molecular Formula	C17H22ClN3O3
Molecular Weight	351.83 g/mol
Synonyms	tert-Butyl N-[[1-[(2-chloropyridine-3-carbonyl)-3-piperidyl]methyl]carbamate; 1-[(2-Chloropyridine-3-carbonyl)piperidin-3-yl]methyl-carbamic Acid tert-Butyl Ester; BOC-Piperidine-Chloropyridine Carboxamide; (3-[[(tert-Butoxycarbonyl)amino]methyl]-1-piperidinyl)(2-chloro-3-pyridinyl)methanone; 1353974-41-0; tert-Butyl ((1-(2-chloronicotinoyl)piperidin-3-yl)methyl)carbamate
EINECS	Contact for details

Quality Control

Our production of [1-(2-Chloro-Pyridine-3-Carbonyl)-Piperidin-3-Ylmethyl]-Carbamic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch traceability are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.