Description

C-[1-(4-Methyl-Benzyl)-Piperidin-2-Yl]-Methylamine Hydrochloride is a high-purity, synthetically derived organic compound supplied as a hydrochloride salt for enhanced stability. This specialized chemical building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It serves as a key intermediate for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Chemistry Development: Serves as a key starting material or intermediate in scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	C-[1-(4-Methyl-Benzyl)-Piperidin-2-Yl]-Methylamine Hydrochloride
CAS No.	1353972-36-7
Molecular Formula	C15H24N2•HCl
Molecular Weight	268.83 g/mol (Free base: 232.36 g/mol)
Synonyms	1-(4-Methylbenzyl)-2-(aminomethyl)piperidine hydrochloride; (1-(4-Methylbenzyl)piperidin-2-yl)methanamine hydrochloride; 2-(Aminomethyl)-1-[(4-methylphenyl)methyl]piperidine hydrochloride; N-[(1-(4-Methylbenzyl)piperidin-2-yl)methyl]amine hydrochloride; C-[1-(p-Methylbenzyl)-2-piperidyl]methylamine HCl; 1353972-36-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our C-[1-(4-Methyl-Benzyl)-Piperidin-2-Yl]-Methylamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each batch. Our quality system supports development under ICH guidelines, and custom synthesis to meet specific pharmacopeial standards (e.g., USP, EP) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.