Description

1-(3-Fluoro-Benzyl)-[1,4]Diazepane Hydrochloride is a high-purity, synthetically derived organic compound supplied as a hydrochloride salt. This specialized chemical building block is valued for its role in advanced pharmaceutical research and development, particularly in medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for creating libraries of novel compounds.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for introducing the 1-(3-fluorobenzyl)-[1,4]diazepane moiety into more complex molecular architectures.
• Process Development & Scale-up: Employed in the optimization and pilot-scale production of potential therapeutic agents.
• Reference Standard: Can be used as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	1-(3-Fluoro-Benzyl)-[1,4]Diazepane Hydrochloride
CAS No.	1353965-37-3
Molecular Formula	C₁₂H₁₆ClFN₂
Molecular Weight	242.72 g/mol
Synonyms	1-[(3-Fluorophenyl)methyl]-1,4-diazepane hydrochloride; 1-(3-Fluorobenzyl)-1,4-diazepane HCl; 1,4-Diazepane, 1-[(3-fluorophenyl)methyl]-, hydrochloride (1:1); 3-Fluorobenzyl-homopiperazine hydrochloride; Homopiperazine, 1-(3-fluorobenzyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-Benzyl)-[1,4]Diazepane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and other relevant analytical techniques. Specifications are designed to meet the stringent requirements of pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.