Description

(4-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride CAS NO 1353962-72-7 is a high-purity, pharmaceutically relevant organic salt, serving as a critical advanced intermediate in modern drug discovery and development. Its value lies in its precise molecular architecture, which is essential for constructing complex active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel central nervous system (CNS) agents and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• API Synthesis: Serves as a crucial precursor in the multi-step manufacturing process of complex Active Pharmaceutical Ingredients (APIs).
• Preclinical & Clinical Development: Supplied in GMP and non-GMP grades to support drug development from discovery through clinical trial material production.
• Contract Research & Manufacturing (CRO/CMO): A reliable raw material for organizations providing outsourced research and production services to the pharmaceutical industry.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(4-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride
CAS No.	1353962-72-7
Molecular Formula	C16H21N2O3·HCl
Molecular Weight	332.81 g/mol (Free base: 289.35 g/mol)
Synonyms	1,4-Benzodioxan-2-carboxylic acid (4-aminomethyl-1-piperidyl) ester hydrochloride; 2,3-Dihydro-1,4-benzodioxin-2-carboxylic acid (4-aminomethyl-1-piperidinyl) ester hydrochloride; (4-Aminomethylpiperidin-1-yl)(2,3-dihydro-1,4-benzodioxin-2-yl)methanone hydrochloride; 1353962-72-7; (4-Aminomethyl-1-piperidyl) 2,3-dihydro-1,4-benzodioxine-2-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride is produced under strict quality management systems. We offer material suitable for research and development, with optional GMP-grade production available to support advanced pharmaceutical applications. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%; Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.