Description

C-[1-(Pyridine-2-Sulfonyl)-Piperidin-2-Yl]-Methylamine Hydrochloride CAS NO 1353958-82-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a key chiral building block for constructing complex molecular architectures in active pharmaceutical ingredient (API) process development.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study enzyme inhibition or receptor binding mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for synthetic organic chemistry projects and the development of new synthetic methodologies.

Basic Information

Product Name	C-[1-(Pyridine-2-Sulfonyl)-Piperidin-2-Yl]-Methylamine Hydrochloride
CAS No.	1353958-82-3
Molecular Formula	C12H19N3O2S • HCl
Molecular Weight	305.82 g/mol (Free base: 269.36 g/mol)
Synonyms	1-(Pyridine-2-sulfonyl)piperidin-2-yl]methanamine hydrochloride; (1-(Pyridin-2-ylsulfonyl)piperidin-2-yl)methanamine HCl; 2-[[(2-Aminomethyl)piperidin-1-yl]sulfonyl]pyridine hydrochloride; C-[1-(2-Pyridylsulfonyl)-2-piperidyl]methylamine hydrochloride; (R/S)-C-[1-(Pyridine-2-sulfonyl)-piperidin-2-yl]-methylamine hydrochloride; 1353958-82-3; PSMA-HCl (abbrev.)
EINECS	Contact for details

Quality Control

Our C-[1-(Pyridine-2-Sulfonyl)-Piperidin-2-Yl]-Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR, MS) to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot. We support development with custom synthesis and scale-up capabilities to meet evolving project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.