Description

(2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-Piperazin-1-Yl-Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those with benzodioxane and piperazine pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• CNS Drug Development: A precursor in the research of compounds targeting neurological receptors and pathways.
• Chemical Synthesis: Serves as a versatile synthon for creating complex molecular libraries for high-throughput screening.
• Academic & Contract Research: Employed in university and CRO settings for exploratory research in organic and bioorganic chemistry.
• Reference Standard: Can be used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	(2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-Piperazin-1-Yl-Methanone Hydrochloride
CAS No.	1353958-63-0
Molecular Formula	C14H17ClN2O3
Molecular Weight	296.75 g/mol
Synonyms	5-(Piperazine-1-carbonyl)-2,3-dihydro-1,4-benzodioxine hydrochloride; 1,4-Benzodioxin-5-yl(piperazin-1-yl)methanone hydrochloride; (2,3-Dihydro-1,4-benzodioxin-5-yl)(piperazin-1-yl)methanone HCl; 5-(Piperazin-1-ylcarbonyl)-2,3-dihydro-1,4-benzodioxine hydrochloride; (2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)(piperazin-1-yl)methanone hydrochloride
EINECS	Contact for details

Quality Control

Our (2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-Piperazin-1-Yl-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.