Description

n-(4-Chloro-Benzyl)-n-Cyclopropyl-2-(3-Hydroxy-Piperidin-1-Yl)-Acetamide is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Chemical Synthesis: Used in organic synthesis for constructing complex molecules featuring cyclopropyl, piperidine, and chlorobenzyl motifs.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development: Employed in the scale-up and route scouting phases for the commercial manufacturing of target APIs.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API production.

Basic Information

Product Name	n-(4-Chloro-Benzyl)-n-Cyclopropyl-2-(3-Hydroxy-Piperidin-1-Yl)-Acetamide
CAS No.	1353954-37-6
Molecular Formula	C17H23ClN2O2
Molecular Weight	322.83 g/mol
Synonyms	N-[(4-Chlorophenyl)methyl]-N-cyclopropyl-2-(3-hydroxypiperidin-1-yl)acetamide; 1-[2-[[(4-Chlorophenyl)methyl](cyclopropyl)amino]-2-oxoethyl]-3-piperidinol; N-Cyclopropyl-N-[(4-chlorophenyl)methyl]-2-(3-hydroxy-1-piperidinyl)acetamide; Acetamide, N-[(4-chlorophenyl)methyl]-N-cyclopropyl-2-(3-hydroxy-1-piperidinyl)-; 1353954-37-6; UNII-8V8N2J6T8K
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-Benzyl)-n-Cyclopropyl-2-(3-Hydroxy-Piperidin-1-Yl)-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with exacting standards for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.