Description

2-Methyl-4-(3-Methyl-Thiophene-2-Carbonyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering significant value in creating novel therapeutic agents with targeted biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development: Serves as a standard or starting material for scaling up and optimizing synthetic routes in pilot plants and manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Methyl-4-(3-Methyl-Thiophene-2-Carbonyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353953-89-5
Molecular Formula	C17H26N2O3S
Molecular Weight	338.47 g/mol
Synonyms	tert-Butyl 2-methyl-4-[(3-methylthiophen-2-yl)carbonyl]piperazine-1-carboxylate; 1-Boc-2-methyl-4-(3-methylthiophene-2-carbonyl)piperazine; 2-Methyl-4-(3-methyl-2-thienylcarbonyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-methyl-4-(3-methylthiophene-2-carbonyl)piperazine; Boc-2-methyl-4-(3-methylthiophene-2-carbonyl)piperazine
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(3-Methyl-Thiophene-2-Carbonyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.