Description

2-Methyl-1-(Toluene-3-Sulfonyl)-Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonamide and piperazine-based structure. This compound is critical for the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery programs.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new drug candidates, especially those targeting neurological and psychiatric disorders.
• Research & Development of Bioactive Molecules: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Precursor for Complex Heterocyclic Compounds: Its reactive sites make it valuable for constructing more complex molecular architectures in organic synthesis.
• Process Chemistry and Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential APIs under cGMP conditions.

Basic Information

Product Name	2-Methyl-1-(Toluene-3-Sulfonyl)-Piperazine Hydrochloride
CAS No.	1353951-47-9
Molecular Formula	C12H19ClN2O2S
Molecular Weight	290.81 g/mol
Synonyms	1-(3-Methylphenyl)sulfonyl-2-methylpiperazine hydrochloride; 2-Methyl-1-(m-tolylsulfonyl)piperazine hydrochloride; 2-Methyl-1-(3-toluenesulfonyl)piperazine HCl; 1-(3-Toluenesulfonyl)-2-methylpiperazine hydrochloride; m-Tolylsulfonyl-2-methylpiperazine hydrochloride; 3-Methylbenzenesulfonyl-2-methylpiperazine hydrochloride; Piperazine, 2-methyl-1-[(3-methylphenyl)sulfonyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Methyl-1-(Toluene-3-Sulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.