Description

1-(Pyridine-2-Sulfonyl)-Piperazine Hydrochloride is a high-purity, synthetic organic compound of significant interest in advanced chemical synthesis. This specialized building block is valued for its unique sulfonamide-linked heterocyclic structure, which is crucial for modulating biological activity and physicochemical properties in target molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and protease inhibitor programs.
• Chemical Biology Probe Synthesis: Used to create tool compounds for studying enzyme function and protein-protein interactions in biological systems.
• Agrochemical Research: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for metal catalysis and coordination chemistry applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	1-(Pyridine-2-Sulfonyl)-Piperazine Hydrochloride
CAS No.	1353948-48-7
Molecular Formula	C9H14ClN3O2S
Molecular Weight	263.74 g/mol
Synonyms	1-(Pyridin-2-ylsulfonyl)piperazine hydrochloride; Piperazine, 1-(2-pyridinylsulfonyl)-, hydrochloride; 2-(Piperazine-1-sulfonyl)pyridine hydrochloride; 1-(Pyridine-2-sulfonyl)piperazine HCl; 1-(2-Pyridylsulfonyl)piperazine hydrochloride; N-(Pyridine-2-sulfonyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyridine-2-Sulfonyl)-Piperazine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.