Description

3-(3-Methyl-Pyrazin-2-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a key building block in the multi-step production of Active Pharmaceutical Ingredients (APIs), especially for small molecule therapeutics.
• Chemical Biology Probes: Employed in the development of chemical probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.

Basic Information

Product Name	3-(3-Methyl-Pyrazin-2-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353946-15-2
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	tert-Butyl 3-[(3-methylpyrazin-2-yl)amino]pyrrolidine-1-carboxylate; 1-Boc-3-[(3-methyl-2-pyrazinyl)amino]pyrrolidine; 3-[(3-Methyl-2-pyrazinyl)amino]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 3-(3-Methyl-pyrazin-2-ylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 3-[(3-methyl-2-pyrazinyl)amino]-1-pyrrolidinecarboxylate; Boc-3-(3-methylpyrazin-2-ylamino)pyrrolidine
EINECS	Contact for details

Quality Control

Our production of 3-(3-Methyl-Pyrazin-2-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management systems, ensuring batch-to-batch consistency suitable for research and cGMP manufacturing. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.