Description

2-Bromo-5-(Bromomethyl)Pyridine Hydrochloride is a high-purity, multi-functional halogenated pyridine derivative. This compound is a critical pharmaceutical intermediate and versatile chemical building block for advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and fungicides due to its reactive bromomethyl and bromo substituents.
• Ligand and Catalyst Development: Used to create functionalized pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the production of functional organic molecules for electronic materials and polymers.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Substitution: The bromomethyl group is highly reactive for further functionalization with various nucleophiles, enabling diverse molecular diversification.

Basic Information

Product Name	2-Bromo-5-(Bromomethyl)Pyridine Hydrochloride
CAS No.	1353945-06-8
Molecular Formula	C6H6Br2N•HCl
Molecular Weight	287.34 g/mol (Free base: 250.93 g/mol)
Synonyms	5-(Bromomethyl)-2-bromopyridine hydrochloride; 2-Bromo-5-(bromomethyl)pyridine HCl; 2-Bromo-5-bromomethylpyridine hydrochloride; (6-Bromo-3-pyridyl)methyl bromide hydrochloride; Pyridine, 2-bromo-5-(bromomethyl)-, hydrochloride; 2,5-Dibromomethylpyridine hydrochloride (common name)
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Bromomethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.