Description

[1-(2-Chloro-Acetyl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-based molecular scaffold. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to ensure the integrity and efficiency of their multi-step synthetic routes, enabling the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and production of Active Pharmaceutical Ingredients (APIs) for central nervous system (CNS) and oncology treatments.
• Protease Inhibitor Development: Serves as a precursor in the creation of protease inhibitors and other enzyme-targeting therapeutic molecules.
• Chemical Biology Research: Employed as a tool compound or a tagged ligand in biochemical assays and target identification studies.
• Custom Synthesis & Contract Manufacturing: A key material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.
• Process Chemistry Optimization: Used in scaling up and optimizing synthetic pathways from laboratory to pilot and commercial scale.

Basic Information

Product Name	[1-(2-Chloro-Acetyl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1353944-51-0
Molecular Formula	C14H25ClN2O3
Molecular Weight	304.81 g/mol
Synonyms	tert-Butyl N-[[1-(2-chloroacetyl)-3-piperidyl]methyl]carbamate; 1-(2-Chloroacetyl)-3-[[(tert-butoxycarbonyl)amino]methyl]piperidine; Carbamic acid, N-[[1-(2-chloroacetyl)-3-piperidinyl]methyl]-, 1,1-dimethylethyl ester; BOC-3-Piperidinemethylamine Chloroacetamide Derivative; (1-(2-Chloroacetyl)piperidin-3-yl)methylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our [1-(2-Chloro-Acetyl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.