Description

4-(2,5-Dichloro-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound is critical for research and development in medicinal chemistry, offering a protected piperazine-dicarboxylate scaffold for constructing novel active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Protease Inhibitor Development: Acts as a precursor or core structure in the development of protease inhibitors due to its piperazine-dicarboxylic acid framework.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for the custom synthesis of complex organic compounds for clients.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying enzyme function and biological pathways.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis projects and methodology development.

Basic Information

Product Name	4-(2,5-Dichloro-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	1353944-24-7
Molecular Formula	C17H22Cl2N2O4
Molecular Weight	389.27 g/mol
Synonyms	1-Boc-4-(2,5-dichlorobenzyl)piperazine-2-carboxylic acid; 4-(2,5-Dichlorobenzyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid; tert-Butyl 4-(2,5-dichlorobenzyl)-3-carboxypiperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2,5-dichlorobenzyl)piperazine-2-carboxylic acid; 4-(2,5-Dichlorobenzyl)piperazine-1,3-dicarboxylic acid 1-tert-butyl ester; 1353944-24-7; 2,5-Dichloro-α-[[1-[(1,1-dimethylethoxy)carbonyl]-3-carboxy-4-piperazinyl]methyl]benzenemethanol (9CI)
EINECS	Contact for details

Quality Control

Our 4-(2,5-Dichloro-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.