Description

4-(2-Cyano-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butylester 3-(2-Cyano-Benzyl) Ester is a sophisticated, multi-functional piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring dual cyano-benzyl and tert-butyl ester protecting groups, which provides exceptional versatility for constructing complex nitrogen-containing heterocycles. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used to develop new active ingredients for crop protection, leveraging its piperazine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and enzyme inhibitors.
• Peptidomimetics & Macrocycle Synthesis: The protected dicarboxylic acid structure is ideal for constructing conformationally constrained peptide analogs.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects requiring complex, multi-step transformations.

Basic Information

Product Name	4-(2-Cyano-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butylester 3-(2-Cyano-Benzyl) Ester
CAS No.	1353944-07-6
Molecular Formula	C27H30N4O4
Molecular Weight	474.56 g/mol
Synonyms	1-tert-Butyl 3-(2-cyanobenzyl) 4-(2-cyanobenzyl)piperazine-1,3-dicarboxylate; 4-(2-Cyanobenzyl)piperazine-1,3-dicarboxylic Acid 1-(1,1-Dimethylethyl) Ester 3-(2-Cyanophenyl)methyl Ester; 1-Boc-3-(2-cyanobenzyl)-4-(2-cyanobenzyl)piperazine-1,3-dicarboxylate; 4-(2-Cyanobenzyl)piperazine-1,3-dicarboxylic Acid 1-tert-Butyl Ester 3-(2-Cyanobenzyl) Ester; Piperazine-1,3-dicarboxylic acid, 4-[(2-cyanophenyl)methyl]-, 1-(1,1-dimethylethyl) 3-[(2-cyanophenyl)methyl] ester
EINECS	Contact for details

Quality Control

Our production of 4-(2-Cyano-Benzyl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butylester 3-(2-Cyano-Benzyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.