Description

4-(6-Ethoxy-Pyrimidin-4-Yl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research and production in the pharmaceutical and biotechnology industries, where precise molecular architecture is required. Our supply ensures the consistent quality and reliability needed for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex piperazine and pyrimidine-containing molecular scaffolds.
• Research & Development (R&D): Serves as a key material in academic and industrial laboratories for exploring new chemical entities and biological activities.
• Process Chemistry: Employed in route scouting and optimization for the efficient, scalable production of active pharmaceutical ingredients (APIs).
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for client-specific synthesis projects under cGMP conditions.

Basic Information

Product Name	4-(6-Ethoxy-Pyrimidin-4-Yl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	1353943-90-4
Molecular Formula	C16H24N4O5
Molecular Weight	352.39 g/mol
Synonyms	1-Boc-4-(6-ethoxypyrimidin-4-yl)piperazine-2-carboxylic acid; 1-tert-Butyl 3-carboxy-4-(6-ethoxypyrimidin-4-yl)piperazine-1-carboxylate; 4-(6-Ethoxy-4-pyrimidinyl)-1-piperazinecarboxylic acid 1-(1,1-dimethylethyl) ester-3-carboxylic acid; 4-(6-Ethoxypyrimidin-4-yl)piperazine-1,3-dicarboxylic acid 1-tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(6-ethoxypyrimidin-4-yl)piperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(6-Ethoxy-Pyrimidin-4-Yl)-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and consistency supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.